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BMJ Journals

Drugs: musculoskeletal and joint diseases

Specific clinical findings, including coma, neck stiffness and seizures, increase the likelihood of haemorrhagic stroke, but no combination of features is definitively diagnostic
Michael D Hill

BMJ Evidence-Based Medicine Dec 2010, 15 (6) 183-184; DOI: 10.1136/ebm1121
High blood pressure while taking antithrombotic medication is associated with an increased risk of developing intracranial haemorrhage
Adam J Rose, Elaine M Hylek

BMJ Evidence-Based Medicine Dec 2010, 15 (6) 189-190; DOI: 10.1136/ebm1123
Intensive lowering of systolic blood pressure to a target of less than 120 mm Hg has no effect on the rate of fatal and non-fatal major cardiovascular events in high-risk patients with type 2 diabetes
Atul Chugh, George Bakris

BMJ Evidence-Based Medicine Oct 2010, 15 (5) 142-143; DOI: 10.1136/ebm1099
Benzodiazepines provide no additional benefit over physiotherapy and analgesia in acute lumbar disc prolapse
Antonio Memeo, Leopoldo Pedretti

BMJ Evidence-Based Medicine Oct 2010, 15 (5) 148-149; DOI: 10.1136/ebm1126
No evidence for switching antidepressants in treatment-resistant depressed patients
Michael E Thase

BMJ Evidence-Based Medicine Aug 2010, 15 (4) 120-121; DOI: 10.1136/ebm1083
Muscle cramps: quinine derivatives likely to be effective but not recommended for routine use due to toxicity; vitamin B complex, naftidrofuryl and calcium channel blockers possibly effective
Gavin Young

BMJ Evidence-Based Medicine Aug 2010, 15 (4) 114-115; DOI: 10.1136/ebm1090
There is a slight increase in incident diabetes risk with the use of statins, but benefits likely outweigh any adverse effects in those with moderate-to-high cardiovascular risk
Lokpal Bhatia, Christopher D Byrne

BMJ Evidence-Based Medicine Jun 2010, 15 (3) 84-85; DOI: 10.1136/ebm1075
The use of diuretics plus calcium channel blockers for hypertension may be associated with a higher risk of myocardial infarction but not stroke compared with the combination of diuretics plus β blockers
Rhonda M Cooper-DeHoff, Carl J Pepine

BMJ Evidence-Based Medicine Jun 2010, 15 (3) 92-93; DOI: 10.1136/ebm1067
Pregabalin similar to lorazepam for alcohol withdrawal symptoms
Giovanni Addolorato, Lorenzo Leggio

BMJ Evidence-Based Medicine Jun 2010, 15 (3) 73; DOI: 10.1136/ebm1069
Telephone-delivered collaborative care for post-CABG depression is more effective than usual care for improving mental-health-related quality of life
Phillip J Tully

BMJ Evidence-Based Medicine Apr 2010, 15 (2) 57-58; DOI: 10.1136/ebm1059

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