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Below knee elastic compression stockings reduced development of the post-thrombotic syndrome in proximal deep venous thrombosis

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 Q In patients with a first episode of acute symptomatic proximal deep venous thrombosis (DVT), do below knee elastic compression stockings prevent the post-thrombotic syndrome (PTS)?

Clinical impact ratings GP/FP/Primary care★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Internal medicine ★★★★★★☆ Haematology ★★★★★☆☆


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

blinded {data collectors, outcome assessors, and monitoring committee}.*

Embedded ImageFollow up period:

mean 49 months (range 6–60 mo).

Embedded ImageSetting:

university hospital in Padua, Italy.

Embedded ImagePatients:

180 patients (mean age 62 y, 57% women) with a first episode of acute symptomatic proximal DVT (confirmed by ultrasonography) who were receiving conventional anticoagulant treatment. Exclusion criteria were recurrent ipsilateral DVT, pre-existing leg ulcers or signs of chronic venous insufficiency, bilateral thrombosis, a short life expectancy, or contraindication for use of stockings.

Embedded ImageInterventions:

daily wearing of below knee, graded, elastic compression stockings …

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  • * See glossary.

  • Information provided by author.

  • For correspondence: Dr P Prandoni, University Hospital of Padua, Padua, Italy. paoloprandoni{at}

  • Source of funding: New Medical Service, Linea Flebologica Flebysan, Rovigo, Italy.