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Q In patients with a first episode of acute symptomatic proximal deep venous thrombosis (DVT), do below knee elastic compression stockings prevent the post-thrombotic syndrome (PTS)?
Clinical impact ratings GP/FP/Primary care★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Internal medicine ★★★★★★☆ Haematology ★★★★★☆☆
METHODS
Design:
randomised controlled trial.
Allocation:
{concealed*}†.
Blinding:
blinded {data collectors, outcome assessors, and monitoring committee}†.*
Follow up period:
mean 49 months (range 6–60 mo).
Setting:
university hospital in Padua, Italy.
Patients:
180 patients (mean age 62 y, 57% women) with a first episode of acute symptomatic proximal DVT (confirmed by ultrasonography) who were receiving conventional anticoagulant treatment. Exclusion criteria were recurrent ipsilateral DVT, pre-existing leg ulcers or signs of chronic venous insufficiency, bilateral thrombosis, a short life expectancy, or contraindication for use of stockings.
Interventions:
daily wearing of below knee, graded, elastic compression stockings …