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Therapeutics
Antenatal infection screening reduced preterm delivery

https://doi.org/10.1136/ebm.10.2.47

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    Kiss H, Petricevic L, Husslein P. Prospective randomised controlled trial of an infection screening programme to reduce the rate of preterm delivery. BMJ 2004;329:371.
    OpenUrlAbstract/FREE Full Text

    
 
 Q In pregnant women, does an antenatal programme of screening and treating vaginal infections reduce the rate of preterm delivery?

    Clinical impact ratings GP/FP/Obstetrics ★★★★★★☆ Obstetrics ★★★★★★☆ Infectious disease ★★★★★★☆

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    {concealed*}†.

    Embedded ImageBlinding:

    blinded {participants and healthcare providers}†.*

    Embedded ImageFollow up period:

    to delivery or miscarriage.

    Embedded ImageSetting:

    25 non-hospital based antenatal clinics in Vienna, Austria.

    Embedded ImageParticipants:

    4429 pregnant women (mean age 29 y) presenting for their routine prenatal visit early in the second trimester without subjective complaints. All women were screened by Gram stain for asymptomatic vaginal infection, which was classified as bacterial vaginosis (BV), vaginal candidiasis, and Trichomonas vaginalis infection.

    Embedded ImageIntervention:

    infection screening programme (n = 2201) or control (n = 2228). For the infection screening programme, women and their obstetricians received the vaginal smear test …

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    Footnotes

    • ↵* See glossary.

    • ↵† Information provided by author.

    • For correspondence: Dr H Kiss, University of Vienna Medical School, Vienna, Austria. herbert.kissmeduniwien.ac.at

    • Sources of funding: Fonds Gesundes Österreich and Federal Ministry of Education, Science, and Culture.

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      BMJ Publishing Group Ltd
      BMJ Evidence-Based Medicine 2005; 10 64-64 Published Online First: 30 Mar 2005. doi: 10.1136/ebm.10.2.64