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Prophylactic use of LMWH plus intermittent pneumatic compression prevented DVT in hip or knee arthroplasty

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 Q In patients receiving primary unilateral total hip or total knee replacement surgery, is prophylactic use of low molecular weight heparin (LMWH) plus intermittent pneumatic compression more effective than LMWH plus graduated compression stockings for reducing deep venous thrombosis (DVT)?

Clinical impact ratings IM/Ambulatory care ★★★★★★☆ Internal medicine ★★★★★★☆ Surgery ★★★★★☆☆ Haematology ★★★★☆☆☆


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:


Embedded ImageFollow up period:

6–12 weeks

Embedded ImageSetting:

a university hospital in Germany

Embedded ImagePatients:

139 patients ⩾18 years of age who were awaiting primary unilateral total hip or knee replacement. Exclusion criteria included a history of cardiac insufficiency and chronic renal insufficiency.

Embedded ImageIntervention:

thromboembolic prophylaxis with LMWH plus intermittent pneumatic compression (n = 70) or LMWH plus graduated compression stockings (class 1, …

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  • * Information provided by author.

  • For correspondence: Dr Y Silbersack, Martin Luther University, Halle/Salle, Germany

  • Source of funding: Aircast Europa GmbH.

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