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Review: oestrogen improves symptoms of overactive bladder in postmenopausal women

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 Q In postmenopausal women with symptoms suggestive of overactive bladder (OAB) (urge or stress incontinence), does oestrogen therapy reduce symptoms more than placebo?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Gynaecology ★★★★★☆☆


Embedded ImageData sources:

studies were identified by searching Medline, EMBASE/Excerpta Medica, Science Citation Index (January 1969 to December 1999), and reference lists of articles; and hand searching urology, gynaecology, gerontology, and primary care medicine journals.

Embedded ImageStudy selection and assessment:

studies in any language were selected if they were randomised controlled trials (RCTs) that were published or presented at a scientific meeting, reported symptoms suggestive of OAB (including frequency, urgency, or urge incontinence), and compared oestrogen with placebo.

Embedded ImageOutcomes:

diurnal frequency, nocturnal frequency, incontinence episodes, urgency, first sensation to void, and bladder capacity. …

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