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Therapeutics
The cognitive behavioural analysis system of psychotherapy prevented recurrence in chronic major depression

https://doi.org/10.1136/ebm.10.3.85

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    Klein DN, Santiago NJ, Vivian D, et al. Cognitive-behavioral analysis system of psychotherapy as a maintenance treatment for chronic depression. J Consult Clin Psychol 2004;72:681–8.
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 Q In patients with chronic major depressive disorder (MDD), does the cognitive behavioural analysis system of psychotherapy [CBASP] prevent recurrence?

    Clinical impact ratings Psychiatry ★★★★★★☆ GP/FP/Mental health ★★★★★☆☆

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    {concealed*}†.

    Embedded ImageBlinding:

    blinded ({data collectors}† and outcome assessors).*

    Embedded ImageFollow up period:

    1 year maintenance phase (after 12 wks in a treatment phase and 16 wks in a continuation phase).

    Embedded ImageSetting:

    12 academic centres in the US.

    Embedded ImagePatients:

    82 patients who were 18–75 years of age (mean age 45 y, 67% women); began the treatment phase with a DSM-IV diagnosis of MDD (duration ⩾2 y) and a score ⩾20 on the 24 item Hamilton Rating Scale for Depression (HRSD-24); and responded to CBASP alone during the treatment …

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    Footnotes

    • ↵* See glossary.

    • ↵† Information provided by author.

    • For correspondence: Dr D N Klein, State University of New York at Stony Brook, Stony Brook, NY, USA. dkleinnotes.cc.sunysb.edu

    • Source of funding: Bristol-Myers Squibb.