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A haemoglobin concentration of 140 g/l was associated with a lower mortality risk than concentrations ⩽120 g/l in older women with disabilities

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 Q Are haemoglobin (Hb) concentrations associated with mortality risk in older, community dwelling women with disabilities?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆Haematology ★★★★☆☆☆ Geriatrics ★★★★★☆☆


Embedded ImageDesign:

cohort study (Women’s Health and Aging Study I).

Embedded ImageSetting:

Baltimore, Maryland, USA.

Embedded ImagePatients:

686 women ⩾65 years of age (mean age 78 y, 72% white), who had a Mini-Mental State Examination score ⩾18 and self reported difficulty performing activities in ⩾2 physical function domains.

Embedded ImageRisk factors:

Hb concentrations.

Embedded ImageOutcomes:

all cause mortality after a maximum of 6 years of follow up (median 5 y).


Cumulative all cause mortality was 31%. A non-linear relation existed between Hb and mortality, with highest mortality risk at extreme Hb concentrations and lowest risk in intermediate Hb concentrations. Mildly low Hb concentrations …

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