THERAPEUTICS
Jahn H, Schick M, Kiefer F, et al. Metyrapone as additive treatment in major depression: a double-blind and placebo-controlled trial. Arch Gen Psychiatry 2004;61:1235–44.
IM/Ambulatory care ★★★★★★★ Mental health ★★★★★★☆ Psychiatry ★★★★★★☆
Koelling TM, Johnson ML, Cody RJ, et al. Discharge education improves clinical outcomes in patients with chronic heart failure. Circulation 2005;111:179–85.
GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★☆☆ Cardiology ★★★★★☆☆
Galbreath AD, Krasuski RA, Smith B, et al. Long-term healthcare and cost outcomes of disease management in a large, randomized, community-based population with heart failure. Circulation 2004;110:3518–26.
GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★☆☆☆ Cardiology ★★★★★☆☆
Le Saux N, Gaboury I, Baird M, et al. A randomized, double-blind, placebo-controlled noninferiority trial of amoxicillin for clinically diagnosed acute otitis media in children 6 months to 5 years of age. CMAJ 2005;172:335–41.
GP/FP/Primary care ★★★★★★☆ Infectious disease ★★★★★☆☆ Paediatrics ★★★★★★☆
Lous J, Burton M, Felding J, et al. Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children. Cochrane Database Syst Rev 2005;(1):CD001801.
GP/FP/Primary care ★★★★★★☆ Paediatrics ★★★★★★☆
Craig WR, Hanlon-Dearman A, Sinclair C, et al. Metoclopramide, thickened feedings, and positioning for gastro-oesophageal reflux in children under two years. Cochrane Database Syst Rev 2004;(4):CD003502.
GP/FP/Primary care ★★★★★★☆ Paediatrics ★★★★★★☆
Hall SM, Humfleet GL, Reus VI, et al. Extended nortriptyline and psychological treatment for cigarette smoking. Am J Psychiatry 2004;161:2100–7.
GP/FP/Primary care ★★★★★★☆ Mental health ★★★★★☆☆
Mueller C, Laule-Kilian K, Scholer A, et al. Use of B-type natriuretic peptide for the management of women with dyspnea. Am J Cardiol 2004;94:1510–4.
Internal medicine ★★★★★★☆ Cardiology ★★★★★☆☆ Respirology ★★★★★☆☆
Shuster S, Meynadier J, Kerl H, et al. Treatment and prophylaxis of seborrheic dermatitis of the scalp with antipityrosporal 1% ciclopirox shampoo. Arch Dermatol 2005;141:47–52.
Dermatology ★★★★★★☆
Santos JB, de Jesus AR, Machado PR, et al. Antimony plus recombinant human granulocyte-macrophage colony-stimulating factor applied topically in low doses enhances healing of cutaneous Leishmaniasis ulcers: a randomized, double-blind, placebo-controlled study. J Infect Dis 2004;190:1793–6.
Infectious disease ★★★★★★☆ Tropical & travel medicine ★★★★★☆☆ Dermatology ★★★★★★☆
Kenyon S, Boulvain M, Neilson J. Antibiotics for preterm rupture of the membranes: a systematic review. Obstet Gynecol 2004;104:1051–7.
Obstetrics ★★★★★★☆ Infectious disease ★★★★★★☆
Ettinger B, Ensrud KE, Wallace R, et al. Effects of ultralow-dose transdermal estradiol on bone mineral density: a randomized clinical trial. Obstet Gynecol 2004;104:443–51.
GP/FP/Primary care ★★★★★☆☆ Endocrine ★★★★★★☆ Rheumatology ★★★★★★☆
Green C, Colquitt JL, Kirby J, et al. Clinical and cost-effectiveness of once-daily versus more frequent use of same potency topical corticosteroids for atopic eczema: a systematic review and economic evaluation. Health Technol Assess 2004;8:1–120.
GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★☆☆☆ Dermatology ★★★★☆☆☆
Holland R, Lenaghan E, Harvey I, et al. Does home based medication review keep older people out of hospital The HOMER randomised controlled trial. BMJ 2005;330:293.
GP/FP/Primary care ★★★★★☆☆ Geriatrics ★★★★★★☆
Shen WK, Decker WW, Smars PA,et al. Syncope Evaluation in the Emergency Department Study (SEEDS): a multidisciplinary approach to syncope management. Circulation 2004;110:3636–45.
GP/FP/Primary care ★★★★★☆☆ Emergency medicine ★★★★★☆☆ Internal medicine ★★★★★★☆ Cardiology ★★★★★★☆ Neurology ★★★★★★☆
Man WD, Polkey MI, Donaldson N, et al. Community pulmonary rehabilitation after hospitalisation for acute exacerbations of chronic obstructive pulmonary disease: randomised controlled study. BMJ 2004;329:1209.
GP/FP/Primary care ★★★★★☆☆ Internal medicine ★★★★★★☆ Respirology ★★★★★★☆
Willemse GR, Smit F, Cuijpers P, et al. Minimal-contact psychotherapy for sub-threshold depression in primary care. Randomised trial. Br J Psychiatry 2004;185:416–21.
GP/FP/Primary care ★★★★☆☆☆ Mental health ★★★★★★☆ Psychiatry ★★★★★★☆
Schernhammer ES, Colditz GA. Suicide rates among physicians: a quantitative and gender assessment (meta-analysis). Am J Psychiatry 2004;161:2295–302.
GP/FP/Primary care ★★★★★☆☆ Mental health ★★★★☆☆☆
Williams N, Ogden J. The impact of matching the patient’s vocabulary: a randomized control trial. Fam Pract 2004;21:630–5.
GP/FP/Primary care ★★★★★☆☆
Prochazka AV, Kick S, Steinbrunn C, et al. A randomized trial of nortriptyline combined with transdermal nicotine for smoking cessation. Arch Intern Med 2004;164:2229–33.
GP/FP/Primary care ★★★★★☆☆ Respirology ★★★★★☆☆
Perez-Gomez F, Alegria E, Berjon J, et al. Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation: a randomized multicenter study. J Am Coll Cardiol 2004;44:1557–66.
IM/Ambulatory care ★★★★★☆☆ Cardiology ★★★★★★☆
Lee H, Ernst E. Acupuncture for labor pain management: a systematic review. Am J Obstet Gynecol 2004;191:1573–9.
GP/FP/Anaesthesia ★★★★★☆☆ GP/FP/Obstetrics ★★★★★☆☆ Obstetrics ★★★★★★☆
Rao S, Bhatt J, Houghton C, et al. An improved urine collection pad method: a randomised clinical trial. Arch Dis Child 2004;89:773–5.
Infectious disease ★★★★★☆☆ Paediatrics ★★★★★★☆
Grant AM, Scott NW, O’Dwyer PJ, et al. Five-year follow-up of a randomized trial to assess pain and numbness after laparoscopic or open repair of groin hernia. Br J Surg 2004;91:1570–4.
Surgery ★★★★★☆☆
Ogilvie D, Egan M, Hamilton V, et al. Promoting walking and cycling as an alternative to using cars: systematic review. BMJ 2004;329:763.
GP/FP/Primary care ★★★★☆☆☆
AETIOLOGY
Henriksen TB, Hjollund NH, Jensen TK, et al. Alcohol consumption at the time of conception and spontaneous abortion. Am J Epidemiol 2004;160:661–7.
GP/FP/Primary care ★★★★★★☆ Obstetrics ★★★★★★☆
Strandberg TE, Strandberg A, Rantanen K, et al. Low cholesterol, mortality, and quality of life in old age during a 39-year follow-up. J Am Coll Cardiol 2004;44:1002–8.
GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★☆☆ Cardiology ★★★★★★☆
Shahinian VB, Kuo YF, Freeman JL, et al. Risk of fracture after androgen deprivation for prostate cancer. N Engl J Med 2005;352:154–64.
Oncology ★★★★★★☆ Rheumatology ★★★★☆☆☆
Cullinan P, MacNeill SJ, Harris JM, et al. Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study. Thorax 2004;59:855–61.
GP/FP/Primary care ★★★★★☆☆ Allergy & immunology ★★★★★★☆ Immunology ★★★★★★☆ Respirology ★★★★★★☆ Paediatrics ★★★★☆☆☆
Parker SK, Schwartz B, Todd J, et al. Thimerosal-containing vaccines and autistic spectrum disorder: a critical review of published original data. Pediatrics 2004;114:793–804.
GP/FP/Primary care ★★★★★☆☆ Paediatrics ★★★★★★☆