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The following articles are abstracted in the July/August 2005 issue of ACP Journal Club. The declarative title of each abstract as published in ACP Journal Club precedes the article citation.
THERAPEUTICS
▸ Review: Population-based screening for abdominal aortic aneurysm reduces cause-specific mortality in older men
▸ Review: Somatostatin and its analogues do not reduce mortality in acute bleeding esophageal varices
▸ Review: Noninvasive positive pressure ventilation reduces intubation and length of ICU stay in acute respiratory failure
▸ Review: High-dose vitamin E supplementation is associated with increased all-cause mortality
▸ Review: Adding long-acting β2-agonists to inhaled corticosteroids reduces asthma exacerbations more than adding antileukotrienes
▸ Review: Atypical antipsychotic drugs modestly improve neuropsychiatric symptoms of dementia
▸ Review: Little evidence supports the efficacy of major commercial and organized self-help weight loss programs
▸ Review: Bisphosphonates are modestly better than placebo for relieving painful bone metastases
▸ Reviparin reduced a composite endpoint of death, reinfarction, stroke, and ischemia at 7 and 30 days after acute MI
▸ A glucose-insulin-potassium infusion did not reduce mortality, cardiac arrest, or cardiogenic shock after acute MI
▸ Nasogastric and nasojejunal feeding did not differ for acute phase response or pain in severe acute pancreatitis
▸ Pegaptanib was effective and safe without a dose-response relation in neovascular age-related macular degeneration
▸ Patient self-management of anticoagulants reduced arterial thromboembolism and adverse effects
▸ Physician accuracy to predict successful treatment response in suspected obstructive sleep apnea did not differ between home monitoring and polysomnography
AETIOLOGY
▸ Inhaled corticosteroids did not increase nonvertebral fractures in adults with asthma or chronic obstructive pulmonary disease
▸ Risk for injury in the elderly may vary by benzodiazepine, independent of half-life
CLINICAL PREDICTION GUIDE
▸ A risk stratification tool predicted in-hospital mortality in acute decompensated heart failure