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Q In children with acute undifferentiated abdominal pain, is buccal oxycodone more effective than placebo for reducing pain without altering clinical signs or outcome?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Emergency medicine ★★★★★★☆ Paediatrics ★★★★★★☆
METHODS
Design:
randomised placebo controlled trial.
Allocation:
unclear allocation concealment.*
Blinding:
blinded (patients and healthcare providers).*
Follow up period:
3.5 hours.
Setting:
a hospital in Finland.
Patients:
63 children 4–15 years of age (mean age 11 y, 51% boys) who presented to the emergency department with undifferentiated acute abdominal pain for <7 days, and had a pain score ⩾5 cm on a 10 cm visual analogue scale.
Intervention:
bucally injected oxycodone hydroxide, 0.1 mg/g-1 (Oxanest 10 mg/ml-1 solution; Leiras Oy, Turku, Finland) (n = 32) or placebo (same …
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