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  • Review: α glucosidase inhibitors improve glycaemic control but have uncertain effects on patient-important outcomes in type 2 diabetes

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Therapeutics
Review: α glucosidase inhibitors improve glycaemic control but have uncertain effects on patient-important outcomes in type 2 diabetes

https://doi.org/10.1136/ebm.10.6.174

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    Van de Laar FA, Lucassen PL, Akkermans RP, et al. Alpha-glucosidase inhibitors for type 2 diabetes mellitus. Cochrane Database Syst Rev 2005;(2):CD003639.

    
 
 Q In patients with type 2 diabetes mellitus, are α glucosidase inhibitors effective for improving glycaemic control?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★☆☆ Endocrine ★★★★★☆☆

    METHODS

    Embedded ImageData sources:

    Medline (to April 2003), EMBASE/Excerpta Medica (to April 2003), the Cochrane Central Register of Controlled Trials (Issue 3, 2003), LILACS (to April 2003), databases of ongoing trials (all to April 2003), Current Contents (to December 2003), contacting experts and manufacturers, and bibliographies of relevant studies.

    Embedded ImageStudy selection and assessment:

    randomised controlled trials (RCTs) in any language with ⩾12 weeks’ duration that compared α glucosidase inhibitor monotherapy with any other intervention in patients with type 2 diabetes and included …

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    Footnotes

    • For correspondence: Dr F Van de Laar, University Medical Centre Nijmegen, Nijmegen, The Netherlands. f.vandelaar{at}hag.umcn.nl

    • Source of funding: no external funding.