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  • Fatty acid supplements did not improve motor function but improved literacy levels in developmental coordination disorder

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Therapeutics
Fatty acid supplements did not improve motor function but improved literacy levels in developmental coordination disorder

https://doi.org/10.1136/ebm.10.6.181

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    Richardson AJ, Montgomery Paul. The Oxford-Durham study: a randomized, controlled trial of dietary supplementation with fatty acids in children with developmental coordination disorder. Pediatrics 2005;115:1360–6.
    OpenUrlAbstract/FREE Full Text

    
 
 Q In children with developmental coordination disorder (DCD), do fatty acid supplements improve motor function, reading and spelling levels, and symptoms of attention deficit/hyperactivity disorder (ADHD)?

    Clinical impact ratings Paediatrics ★★★★★★☆ Psychiatry ★★★★★★☆

    METHODS

    Embedded ImageDesign:

    randomised placebo controlled trial (Oxford-Durham Study).

    Embedded ImageAllocation:

    concealed.*

    Embedded ImageBlinding:

    blinded (patients, clinicians, and outcome assessors).*

    Embedded ImageFollow up period:

    3 months.

    Embedded ImageSetting:

    12 elementary schools in County Durham, UK.

    Embedded ImagePatients:

    117 patients (mean age 8.8 y, 67% boys) who met DSM-IV criteria for DCD and were not receiving any treatment. Exclusion criteria: any major physical or mental health condition (eg, epilepsy, diabetes mellitus, depression, or chronic fatigue syndrome).

    Embedded ImageIntervention:

    fatty acid supplements (2 capsules 3 times per d) (n = 60) or matching placebo (n = 57). The supplements consisted of 80% fish oil (sardine and pilchard) and 20% evening primrose …

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    Footnotes

    • ↵* See glossary.

    • For correspondence: Dr A J Richardson, University Laboratory of Physiology, Oxford, UK. alex.richardson{at}physiol.ox.ac.uk

    • Source of funding: none stated.