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Q In patients referred for non-emergent left sided heart catheterisation, how accurate are the third (S3) and fourth (S4) heart sounds detected by computerised phonocardiography for predicting left ventricular dysfunction?
Clinical impact ratings IM/Ambulatory care ★★★★★☆☆ Cardiology ★★★★★★☆
blinded comparison of S3 and S4 with B type natriuretic peptide (BNP) concentration, left ventricular end diastolic pressure (LVEDP), and left ventricular ejection fraction (LVEF) as reference standards.
a university teaching hospital in the US.
90 patients (mean age 62 y, 61% men) who were referred for elective left sided heart catheterisation. Exclusion criteria included age <18 years and systolic pressure <90 mm Hg.
Description of test:
S3 and S4 were obtained from audioelectrocardiographic data generated by the Audicor System (Audicor, Inovise Medical Inc, Portland, OR, USA), with the audioelectrocardiographic leads attached to V3 and V …
For correspondence: Dr Andrew D Michaels, University of California San Francisco Medical Center, San Francisco, CA USA.
Source of funding: National Institutes of Health Mentored Patient-Oriented Research Career Development Award.