You are here

  • Home
  • Archive
  • Volume 10, Issue 6
  • Third and fourth heart sounds had low sensitivity but moderate to high specificity for predicting left ventricular dysfunction.

Article Text

Article menu
Download PDFPDF
Diagnosis
Third and fourth heart sounds had low sensitivity but moderate to high specificity for predicting left ventricular dysfunction.

https://doi.org/10.1136/ebm.10.6.182

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Marcus GM, Gerber L, McKeown BH, et al. Association between phonocardiographic third and fourth heart sounds and objective measures of left ventricular function. JAMA 2005;293:2238–44.
    OpenUrlCrossRefPubMedWeb of Science

    
 
 Q In patients referred for non-emergent left sided heart catheterisation, how accurate are the third (S3) and fourth (S4) heart sounds detected by computerised phonocardiography for predicting left ventricular dysfunction?

    Clinical impact ratings IM/Ambulatory care ★★★★★☆☆ Cardiology ★★★★★★☆

    METHODS

    Embedded ImageDesign:

    blinded comparison of S3 and S4 with B type natriuretic peptide (BNP) concentration, left ventricular end diastolic pressure (LVEDP), and left ventricular ejection fraction (LVEF) as reference standards.

    Embedded ImageSetting:

    a university teaching hospital in the US.

    Embedded ImagePatients:

    90 patients (mean age 62 y, 61% men) who were referred for elective left sided heart catheterisation. Exclusion criteria included age <18 years and systolic pressure <90 mm Hg.

    Embedded ImageDescription of test:

    S3 and S4 were obtained from audioelectrocardiographic data generated by the Audicor System (Audicor, Inovise Medical Inc, Portland, OR, USA), with the audioelectrocardiographic leads attached to V3 and V …

    View Full Text

    Footnotes

    • For correspondence: Dr Andrew D Michaels, University of California San Francisco Medical Center, San Francisco, CA USA. andrewm{at}medicine.ucsf.edu

    • Source of funding: National Institutes of Health Mentored Patient-Oriented Research Career Development Award.