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Perinatal environmental factors and parental psychopathology were associated with risk of autism in Danish children
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 Q In Danish children, are perinatal factors and parental psychiatric history and social economic status associated with subsequent development of autism?

Clinical impact ratings GP/FP/Mental Health ★★★★★☆☆ Paediatrics ★★★★★★☆ Psychiatry ★★★★★★★

METHODS

Embedded ImageDesign:

a case control study nested within a cohort of all children born in Denmark after 1972.

Embedded ImageSetting:

Denmark

Embedded ImagePatients:

698 children (76% boys, mean age at diagnosis 7.7 y) who were discharged from a Danish psychiatric hospital with a diagnosis of infantile or atypical autism before the end of December 1999 constituted the cases. For each case, 25 controls (total n = 17 450) were identified and individually matched to the cases by sex, birth year, and age in days.

Embedded ImageRisk factors:

perinatal risk factors including delivery and newborn characteristics (eg, fetal …

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