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Multislice computed tomography detected coronary artery disease

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 Q What is the diagnostic accuracy of multislice computed tomography (MSCT) in patients with suspected coronary artery disease (CAD)?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★★☆ Cardiology ★★★★★★☆


Embedded ImageDesign:

blinded comparison of MSCT with conventional invasive coronary angiography.

Embedded ImageSetting:

a university hospital in Ulm, Germany.

Embedded ImagePatients:

103 patients (mean age 62 y, 69% men) with suspected CAD. Exclusion criteria included contraindication to iodinated contrast, renal dysfunction, hyperthyroidism, previous surgical revascularisation, and acute coronary syndrome.

Embedded ImageDescription of test:

all patients received MSCT examinations using a scanner with 16 detector rows (Brilliance 16, Philips Medical Systems, Cleveland, OH, USA). Contrast flow rate was adapted according to a test bolus acquisition. Pitch settings were modified according to …

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  • For correspondence: Dr M H Hoffmann, University Hospital, Ulm, Germany. martin.hoffmann{at}

  • Source of funding: State Government of Baden-Wuerttemberg, Germany.