You are here

Article Text

Article menu
Download PDFPDF
Therapeutics
Glargine dose titration by patients and physicians was equally effective for preventing severe hypoglycaemia

https://doi.org/10.1136/ebm.11.2.46

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Davies M, Storms F, Shutler S, et al. Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine. Diabetes Care 2005;28:1282–8.
    OpenUrlAbstract/FREE Full Text

    
 
 Q In patients with suboptimally controlled type 2 diabetes mellitus, is insulin glargine dose titration by a physician equivalent to titration by the patient for preventing severe hypoglycaemia and improving glycaemic control?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★☆☆ Endocrine ★★★★★★☆

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.*

    Embedded ImageAllocation:

    unclear concealment.*

    Embedded ImageBlinding:

    unblinded.*

    Embedded ImageFollow up period:

    24 weeks.

    Embedded ImageSetting:

    611 centres in 59 countries in Western and Eastern Europe, South America, Asia, and Africa/Middle East.

    Embedded ImagePatients:

    5033 patients ⩾18 years of age (mean age 58 y, 58% women) with suboptimally controlled type 2 diabetes mellitus (required basal long acting insulin for the control of hyperglycaemia) and glycated haemoglobin [HbA1C] concentrations >7.0% and <12.0% and BMI <40 kg/m2. Exclusion criteria included impaired renal function and …

    View Full Text

    Footnotes

    • ↵* See glossary.

    • For correspondence: Dr M Davies, University Hospitals of Leicester, Leicester, UK. melanie.davies{at}uhl-tr.nhs.uk

    • Source of funding: Sanofi-Aventis.

    Linked Articles

    • Glossary
      Glossary
      BMJ Publishing Group Ltd
      BMJ Evidence-Based Medicine 2006; 11 63a-63a Published Online First: 30 Mar 2006. doi: 10.1136/ebm.11.2.63a