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A centralised telephone intervention reduced combined all cause mortality or admission for worsening HF in chronic heart failure

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 Q In patients with chronic heart failure (HF), does a centralised telephone intervention by nurses reduce combined all cause mortality or admission for worsening heart failure?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★★☆ Cardiology ★★★★★★☆


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

blinded (outcome adjudicators {and data analysts}).*

Embedded ImageFollow up period:

mean 16 months (range 7–27 mo).

Embedded ImageSetting:

51 centres (public and private hospitals and ambulatory settings) in Argentina.

Embedded ImagePatients:

1518 outpatients (mean age 65 y, 71% men) who were ⩾18 years of age; had stable HF diagnosed ⩾3 months previously, with no admissions in the past 2 months; and had optimal drug treatment that was not modified for ⩾2 months before the trial. Exclusion criteria included need for >1 medical visit per month; HF related to hypertrophic cardiomyopathy, significant valvular lesion, pericarditis or pericardial tamponade, primary pulmonary hypertension or cor pulmonale, …

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  • * See glossary.

  • Information provided by author.

  • For correspondence: G E S I C A Investigators, c/o Dr H O Grancelli, GESICA Foundation, Buenos Aires, Argentina, gesica{at}

  • Source of funding: GESICA Foundation.

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