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Q In patients with bipolar disorder, is the addition of cognitive therapy to standard care cost effective?
Clinical impact ratings Psychiatry ★★★★★★☆
randomised (allocation concealed*), blinded (outcome assessors),* controlled trial with 30 months’ follow up.
Maudsley and Bethlem NHS Trust, London, UK.
103 outpatients who were 18–70 years of age (mean age 44 y, 56% women), had DSM-IV bipolar I disorder, relapsed frequently despite the use of mood stabilisers (ie, ⩾2 episodes in previous 2 y or ⩾3 episodes in 5 y), and did not currently fulfil criteria for a bipolar episode. Exclusion criteria: actively suicidal (Beck Depression Inventory suicide item scored 3) or met criteria for substance use disorder.
51 patients received cognitive therapy plus standard care, and 52 patients received standard care alone.
number of bipolar free days. Costs related to cognitive therapy and contact with mental …
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