Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Q In patients with early rheumatoid arthritis (RA), does adding low dose prednisolone to the first use of a disease modifying antirheumatic drug (DMARD) improve outcomes?
Clinical impact ratings IM/Ambulatory care ★★★★★★☆ Rheumatology ★★★★★☆☆
randomised controlled trial.
blinded (outcome assessors).*
Follow up period
6 centres in southern Sweden.
259 patients 18–80 years of age (mean age 55 y, 64% women) who were starting treatment with a first DMARD for active RA of ⩽1 year’s duration. Patients with previous DMARD or glucocorticoid treatment, low bone mineral density (BMD), or a history of fragility fracture were excluded.
prednisolone, 7.5 mg daily for 2 years (n = 124), or no prednisolone (n = 135). The choice of DMARD (mainly methotrexate or sulfasalazine) was at the attending physician’s discretion. All patients also received calcium, 1000 mg daily.
change in joint damage in the hands and …