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Q In older patients with iron deficiency anaemia, can low dose iron supplementation safely replace conventional doses of iron?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Haematology ★★★★★★★ Geriatrics ★★★★★☆☆
randomised controlled trial.
unclear allocation concealment.*
Follow up period
a geriatric ward in a hospital in Rehovot, Israel.
90 patients ⩾80 years of age (mean age 85 y, 59% women) who were admitted to hospital with a diagnosis of anaemia (haemoglobin concentration 80 [5.0] to 119 g/l [7.4 mmol/l]) and ferritin concentration <40 ng/ml. Exclusion criteria were vitamin B12 deficiency, severe systemic illness, cancer, renal failure, iron therapy or blood transfusion within the previous week, coeliac disease, active known gastrointestinal blood loss, or acute infection.
elemental iron, 15 mg (n = 30), 50 mg (n = 30), or 150 mg (n = 30) per day. Low iron doses (15 and …