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Therapeutics
Review: self monitoring increases the efficacy and safety of anticoagulant therapy
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https://doi.org/10.1136/ebm.11.4.103

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    Heneghan C, Alonso-Coello P, Garcia-Alamino JM, et al. Self-monitoring of oral anticoagulation: a systematic review and meta-analysis. Lancet 2006;367:404–11.
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 Q In patients receiving oral anticoagulant therapy, how do the safety and efficacy of self monitoring compare with management by healthcare professionals?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Internal medicine ★★★★★★☆ Haematology ★★★★★☆☆

    METHODS

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    Medline, EMBASE/Excerpta Medica, and CINAHL (2005); Cochrane Central Register of Controlled Trials; Cochrane Library (issue 2, 2005); UK National Research Register; Trials Central; bibliographies of retrieved studies; manufacturers of home monitors; and experts in the field.

    Embedded ImageStudy selection and assessment

    randomised controlled trials (RCTs) that compared self testing (only) or self management (testing and dose adjustment) with management by healthcare professionals (control group) in adults or children who were receiving oral anticoagulation therapy for any indication. 14 RCTs (n = 3049, mean age range 42–75 y) met the selection criteria. Quality …

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