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Q In children with moderate to severe atopic eczema, are wet wrap bandages more effective than topical ointments alone for maintenance treatment?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Paediatrics ★★★★☆☆☆
METHODS
Design:
randomised controlled trial.
Allocation:
unclear concealment.*
Blinding:
blinded (scoring nurse).*
Follow up period:
1 month.
Setting:
a secondary care paediatric department at Fairfield General Hospital, Bury in Greater Manchester, UK.
Patients:
50 children 3–60 months of age who were diagnosed with moderate to severe atopic eczema according to Hanifin and Rajka criteria, and had a severity rating of moderate or severe according to the SCORing Atopic Dermatitis (SCORAD) index (score ⩾ 15). Children with active skin infection at enrolment, previous allergic reactions to proposed trial treatments, or eczema predominantly on the face were excluded.
Intervention:
wet wraps (n = 28) or usual care (n = 22) for 4 weeks. Wet wrap bandages were initially applied 24 hours/day over …
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