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Q In patients with newly diagnosed chronic kidney disease (CKD) followed for 5 years, what are the risks of renal replacement therapy (RRT) and death? What factors predict these outcomes?
Clinical impact ratings Nephrology ★★★★★★☆
inception cohort followed for 4.5–6.5 years (median 5 y).
60 hospitals in Sweden.
920 patients 18–74 years of age (18% <45 y, 41% 45–64 y, and 41% ⩾65 y; 65% men) diagnosed with significant CKD (serum creatinine concentration >3.4 mg/dl [300 µmol/l] in men or >2.8 mg/dl [250 µmol/l] in women for the first time and permanently during the inclusion period), identified from the records of 68 medical laboratories that covered most inpatient and outpatient care in Sweden over a 2 year period. Patients with kidney transplants or elevated creatinine concentrations because of dehydration, acute renal failure, or terminal …
For correspondence: Dr M Evans, Karolinska University Hospital, Huddinge, Sweden.
Source of funding: Internal Epidemiology Institute.