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Q In patients taking warfarin, how accurate is the Outpatient Bleeding Risk Index for predicting major bleeding?
Clinical impact ratings Internal medicine ★★★★★★☆ Cardiology ★★★★★★☆ Haematology ★★★★★★☆ Neurology ★★★★★☆☆
METHODS
Design:
retrospective cohort study to validate the previously developed Outpatient Bleeding Risk Index in a veteran population.
Setting:
a pharmacist run anticoagulation clinic at the Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA.
Patients:
1269 patients (mean age 68 y, 92% men, 82% white) taking warfarin for <1 to >36 months.
Description of prediction guide:
the Outpatient Bleeding Risk Index (range 0–4) is a summation of 4 factors: (i) age (⩾65 y = 1), (ii) history of stroke = 1, (iii) history of gastrointestinal bleeding = 1, and (iv) presence of ⩾1 serious comorbidity (recent myocardial …
Footnotes
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For correspondence: Dr S L Aspinall, VA Pittsburgh Healthcare System, PA, USA. sherrie.aspinall{at}med.va.gov
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Source of funding: no external funding.
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