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Q In patients with mild to moderate asthma, what is the efficacy and safety of budesonide plus formoterol in a single inhaler for both maintenance therapy and symptom relief compared with budesonide for maintenance therapy plus terbutaline for symptom relief?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Allergy & immunology ★★★★★★★ Respirology ★★★★★☆☆
METHODS
Design:
randomised controlled trial.
Allocation:
concealed (unclear).*
Blinding:
blinded (patients).*
Follow up period:
6 months.
Setting:
77 centres in Argentina, Brazil, China, Denmark, Indonesia, Norway, the Philippines, Spain, and Sweden.
Patients:
697 patients 11–79 years of age (mean age 38 y, 61% women) with asthma for ⩾6 months. Exclusion criteria included systemic corticosteroids or inhaled cromones in the past 30 days, recent respiratory infection, smoking history >10 pack years, and failure to complete a …
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