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Therapeutics
Laparoscopic surgery was better than an intensive non-surgical intervention for weight loss in mild to moderate obesity

https://doi.org/10.1136/ebm.11.5.146

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    O’Brien PE, Dixon JB, Laurie C, et al. Treatment of mild to moderate obesity with laparoscopic adjustable gastric banding or an intensive medical program: a randomized trial. Ann Intern Med 2006;144:625–33.
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 Q In patients with mild to moderate obesity, is laparoscopic gastric band (LGB) surgery more effective than a non-surgical diet and lifestyle intervention for promoting weight loss?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Endocrine ★★★★★★☆ Surgery—gastrointestinal ★★★★★★☆

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    concealed.*

    Embedded ImageBlinding:

    unblinded.*

    Embedded ImageFollow up period:

    2 years.

    Embedded ImageSetting:

    a community clinic, clinics in a university department of surgery, and a private community hospital in Australia.

    Embedded ImagePatients:

    80 patients 20–50 years of age (mean age 41 y, 76% women) who had a body mass index (BMI) 30–35 kg/m2; had obesity related comorbidities (⩾1 of gastro-oesophageal reflux disease, hypertension, dyslipidaemia, diabetes, or obstructive sleep apnoea), psychosocial conditions, or severe physical limitations; and had attempted to lose weight in the past 5 years. Exclusion criteria were contraindications to treatment or bariatric surgery or participation in a physician supervised programme of …

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    Footnotes

    • ↵* See glossary.

    • For correspondence: Professor P O’Brien, Monash University Medical School, Melbourne, Victoria, Australia. paul.obrien{at}med.monash.edu.au

    • Source of funding: INAMED Health; Novartis; US Surgical Corp.

    Linked Articles

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      BMJ Publishing Group Ltd
      BMJ Evidence-Based Medicine 2006; 11 159a-159a Published Online First: 29 Sep 2006. doi: 10.1136/ebm.11.5.159a