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Response to a 2 week continuous positive airway pressure trial accurately identified patients with obstructive sleep apnoea syndrome

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 Q In patients with suspected obstructive sleep apnoea syndrome (OSA), does a self reported positive response to a 2 week continuous positive airway pressure (CPAP) trial with >2 hours of documented CPAP use per night accurately identify patients with OSA?

Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Internal medicine ★★★★★☆☆ Respirology ★★★★★★☆


Embedded ImageDesign:

blinded comparison of response to a 2 week CPAP trial with polysomnography.

Embedded ImageSetting:

a sleep disorder centre in Zurich, Switzerland.

Embedded ImagePatients:

76 patients (mean age 52 y, 80% men) with suspected OSA (habitual snorer, complaint of daytime sleepiness, and an Epworth sleeping scale score ⩾8). Exclusion criteria included a contraindication for CPAP (unstable congestive heart failure, significant lung disease, or obesity hypoventilation); significant nasal obstruction; a history of any sleep disease and CPAP treatment; or a diagnosis of an internal medical, neurological, or psychiatric disease …

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  • For correspondence: Dr K E Bloch, University Hospital of Zurich, Zurich, Switzerland. pneubloc{at}

  • Source of funding: Lung Leagues of Zurich and Schaffhausen.