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Q In patients with acute bacterial conjunctivitis, is antibiotic therapy better than placebo?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Emergency medicine ★★★★★★★ Infectious disease ★★★★★☆☆ Paediatrics ★★★★★☆☆
Medline, EMBASE/Excerpta Medica, and PubMed (all to January 2006); Cochrane Central Register of Controlled Trials (including Cochrane Eyes and Vision Group Trials Register) (issue 4, 2005); SIGLE (up to March 2005); National Research Register (issue 4, 2005); reference lists; authors and investigators of relevant studies; Science Citation Index; and pharmaceutical companies.
Study selection and assessment:
double blind randomised controlled trials (RCTs) that compared any form of antibiotic treatment (including topical, systemic, and combination) with placebo for acute bacterial conjunctivitis. 5 RCTs (n = 1034, >1 mo of age) met the selection criteria; their interventions …
For correspondence: Professor A Sheikh, University of Edinburgh, Edinburgh, UK.
Source of funding: no external funding.
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