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Therapeutics
Review: planned early birth after prelabour rupture of membranes at term has benefits for mother and infant

https://doi.org/10.1136/ebm.12.1.16

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    Dare MR, Middleton P, Crowther CA, et al. Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more). Cochrane Database Syst Rev 2006;(1):CD005302.

    
 
 Q In pregnant women with prelabour rupture of membranes (PROM) at term, is planned early birth better for the mother and infant than expectant management?

    Clinical impact ratings Obstetrics ★★★★★★★ Paediatrics ★★★★★☆☆ Infectious disease ★★★★☆☆☆

    METHODS

    Embedded ImageData sources:

    Medline, EMBASE/Excerpta Medica, Cochrane Pregnancy and Childbirth Group Trials Register (November 2004), Cochrane Central Register of Controlled Trials (issue 4, 2004), and reference lists.

    Embedded ImageStudy selection and assessment:

    randomised and quasi-randomised controlled trials (RCTs) that compared planned early birth (intervention implemented within 24 h) and expectant management (no intervention for ⩾24 h) in pregnant women with PROM at ⩾37 weeks’ gestation. 12 RCTs (n = 6846 women) reporting 13 comparisons met the selection criteria. The active management intervention used was induction of labour with oxytocin in 7 RCTs, prostaglandin in 5 RCTs, and caulophyllum in 1 …

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    Footnotes

    • For correspondence: MsP Middleton, University of Adelaide, Adelaide, South Australia, Australia. Philippa.middleton{at}adelaide.edu.au

    • Source of funding: National Health Service Programme for Research & Development.