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Periodic telephone counselling for polypharmacy improved compliance and reduced mortality

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 Q In patients receiving polypharmacy, does periodic telephone counselling by a pharmacist improve compliance and reduce mortality?

Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ Internal Medicine ★★★★★☆☆


Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:


Embedded ImageFollow up period:

2 years or until death (mean 23.2 mo).

Embedded ImageSetting:

specialist medical clinics in the Prince of Wales Hospital in Hong Kong, China.

Embedded ImagePatients:

patients who were prescribed ⩾5 drugs on ⩾2 consecutive clinic visits were assessed for compliance with the drug regimen. 442 patients 34–96 years of age (mean age 71y, 51% women) who were non-compliant enrolled in the study 12–16 weeks later. Patients were excluded if they received supervised treatment in nursing homes, were deaf or mute, had dementia or other psychological disorders, or spoke non-Cantonese dialects or other languages.

Embedded ImageIntervention:

telephone intervention (n = 219) or no …

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  • * See glossary.

  • Information provided by author.

  • For correspondence: Dr J C Chan, Chinese University of Hong Kong, China. jchan{at}

  • Sources of funding: Hong Kong Government Health Care and Promotion Fund and MSD International.

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