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Review: children <2 years of age with bilateral acute otitis media and children with otorrhoea benefit most from antibiotics

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 Q In children with acute otitis media (AOM), which subgroups of children benefit from treatment with antibiotics?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Infectious disease ★★★★★★☆ Surgery—ear nose throat ★★★★★★☆ Paediatrics ★★★★★☆☆


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Cochrane Library, PubMed, EMBASE/Excerpta Medica, and proceedings of international symposia.

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) that compared antibiotics with placebo or no treatment in children 0–12 years of age with AOM and assessed pain and fever. 6 RCTs (n = 1643, mean age 3.4 y [range 0–11], 50% boys) met the selection criteria, and the authors were willing to supply raw data. In a quality assessment based on …

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  • For correspondence: Dr M M Rovers, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands. M.Rovers{at}

  • Sources of funding: Dutch College of General Practitioners and the Netherlands Organisation for Health Research and Development.