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Q In women who are 40 years of age, does annual mammographic screening reduce breast cancer mortality after 10 years?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Gynaecology ★★★★★★☆ Oncology ★★★★★☆☆
randomised controlled trial (Age trial).
Follow up period:
mean 10.7 years.
23 National Health Service breast screening units in England, Wales, and Scotland.
160 921 women 39–41 years of age (mean age 40 y).
women who were allocated to the intervention group (n = 53 914) were offered annual screening by mammography up to and including the calendar year of their 48th birthday. Women who were allocated to the control group (n = 107 007) received usual medical care.
breast cancer mortality and all cause mortality. …
↵* See glossary.
For correspondence: Dr S Moss, Institute of Cancer Research, Sutton, UK.
Sources of funding: Medical Research Council and Cancer Research and US National Cancer Research Institute
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