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  • Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection

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Therapeutics
Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection

https://doi.org/10.1136/ebm.12.3.84

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    Tong JL, Ran ZH, Shen J, et al. Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther 2007;25:155–68.
    OpenUrlPubMedWeb of Science

    
 
 Q In patients with Helicobacter pylori infection, do probiotics improve eradication rates and reduce side effects of anti-H pylori treatment?

    Clinical impact ratings Gasterenterology ★★★★★★☆ Infectious disease ★★★★★☆☆

    METHODS

    Embedded ImageData sources:

    PubMed, EMBASE/Excerpta Medica, Science Citation Index, and Chinese Biomedical Database (all to October 2006); Cochrane Controlled Trials Register (Issue 2, 2006); reference lists of retrieved articles; abstracts of major gastroenterological meetings; and authors in the field.

    Embedded ImageStudy selection and assessment:

    randomised controlled trials (RCTs) published in English or Chinese that compared an eradication regimen consisting of proton pump inhibitors and 2 antibiotics plus probiotics with the same eradication regimen plus placebo or no additional treatment in patients of any age who had never been treated …

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    Footnotes

    • For correspondence: Dr Z H Ran, Shanghai Jiao Tong University, Shanghai, China. z-ran{at}online.sh.cn

    • Source of funding: Shanghai Leading Academic Discipline Project.