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Q In patients with Helicobacter pylori infection, do probiotics improve eradication rates and reduce side effects of anti-H pylori treatment?
Clinical impact ratings Gasterenterology ★★★★★★☆ Infectious disease ★★★★★☆☆
METHODS
Data sources:
PubMed, EMBASE/Excerpta Medica, Science Citation Index, and Chinese Biomedical Database (all to October 2006); Cochrane Controlled Trials Register (Issue 2, 2006); reference lists of retrieved articles; abstracts of major gastroenterological meetings; and authors in the field.
Study selection and assessment:
randomised controlled trials (RCTs) published in English or Chinese that compared an eradication regimen consisting of proton pump inhibitors and 2 antibiotics plus probiotics with the same eradication regimen plus placebo or no additional treatment in patients of any age who had never been treated …
Footnotes
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For correspondence: Dr Z H Ran, Shanghai Jiao Tong University, Shanghai, China. z-ran{at}online.sh.cn
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Source of funding: Shanghai Leading Academic Discipline Project.