Article Text

Download PDFPDF
Review: flight times >8 hours and presence of risk factors for VTE increases travel related VTE

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

 Q What are the risk factors for travel related venous thromboembolism (VTE)? Which preventive treatments are effective?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Haematology ★★★★★★☆ IM/Ambulatory care ★★★★★☆☆ Tropical & travel Medicine ★★★★★☆☆


Embedded ImageData sources:

Medline (1966 to December 2005), Cochrane Central Register of Controlled Trials, Database of Abstracts of Reviews of Effects, and bibliographies of relevant studies.

Embedded ImageStudy selection and assessment:

case control or cohort studies and randomised controlled trials (RCTs) that evaluated any form of travel as a risk factor of VTE or preventive measures for travel related VTE. Case reports, abstracts, and subgroup analyses of previously published studies were excluded. 25 studies met the selection criteria: 6 case control studies (n = 207–988), 10 cohort studies (n = 320 to >135 million), and 9 RCTs (n = 186–833); most studies evaluated air travel. The interventions evaluated in the 9 RCTs were low molecular weight heparin, aspirin, graduated compression stockings (12–30 mm Hg at …

View Full Text


  • For correspondence: Dr J T Philbrick, University of Virginia Health Sciences Center, Charlottesville, VA, USA. jtp9b{at}

  • Sources of funding: no external funding.