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Therapeutics
The Atkins diet led to more weight loss than the Zone diet in overweight and obese premenopausal women at 12 months

https://doi.org/10.1136/ebm.12.5.138

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    Gardner CD, Kiazand A, Alhassan S, et al. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA 2007;297:969–77.
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 Q In overweight or obese premenopausal women, how do the Atkins; Zone; Lifestyle, Exercise, Attitudes, Relationships, and Nutrition (LEARN); and Ornish diets compare for weight loss?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Obesity—surgeon ★★★★★★☆ Obesity—physician ★★★★★☆☆

    METHODS

    Embedded ImageDesign:

    randomised controlled trial (The Atkins, Traditional, Ornish, Zone [A TO Z] Weight Loss Study).

    Embedded ImageAllocation:

    unclear allocation concealment.*

    Embedded ImageBlinding:

    blinded {data collectors, data analysts, and data safety and monitoring committee}†.*

    Embedded ImageFollow up period:

    12 months.

    Embedded ImageSetting:

    USA.

    Embedded ImagePatients:

    311 premenopausal women 25–50 years of age (mean age 41 y, 71% white) who were overweight or obese (body mass index [BMI] 27–40 kg/m2), had stable body weight in the past 2 months, and stable medications for ⩾3 months. Exclusion criteria included diabetes; hypertension; …

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    Footnotes

    • ↵* See glossary.

    • ↵† Information provided by author.

    • For correspondence: Dr C D Gardner, Stanford University Medical School, Stanford, California, USA. cgardner{at}stanford.edu

    • Sources of funding: National Institutes of Health; Community Foundation of Southeastern Michigan; Human Health Services.

    Linked Articles

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      BMJ Publishing Group Ltd
      BMJ Evidence-Based Medicine 2007; 12 160-160 Published Online First: 01 Oct 2007. doi: 10.1136/ebm.12.5.160