METHODS

Design:

randomised controlled trial.

Allocation:

concealed.*

Blinding:

blinded (outcome assessor).*

Follow up period:

12 weeks.

Setting:

4 hospitals in Indianapolis, Indiana, USA.

Patients:

188 patients ⩾18 years of age (mean age 60 y, 54% women) who had major (74%) or minor (26%) depression after ischaemic stroke (patients were identified at the time of stroke and screened for depression 1–2 mo later), no severe language or cognitive impairment, and a life expectancy ⩾6 months. Exclusion criteria included active psychosis, suicidality, substance abuse, use of a monoamine oxidase inhibitor, and pregnancy.

Intervention:

the “Activate–Initiate–Monitor” care management intervention (n = 94) or usual care (n = 94). The intervention, conducted by nurse care …