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Q In patients with out of hospital cardiac arrest, is an escalating higher energy regimen better than a fixed lower energy regimen for arrhythmia termination with an automated external defibrillator (AED) using a biphasic waveform?
Clinical impact ratings Emergency medicine ★★★★★★☆ Internal medicine ★★★★★★☆ Cardiology ★★★★★★☆
randomised controlled trial.
blinded (healthcare providers, patients, data collectors, and outcome assessors).*
to death or hospital discharge.
out of hospital locations in 3 Canadian cities.
221 patients ⩾8 years of age (mean age 66 y, 80% men) who had out of hospital cardiac arrest and required defibrillation (for ventricular fibrillation [VF] or pulseless ventricular tachycardia) and whose initial defibrillation was provided by first responders using an AED. Exclusion criteria included terminal illness, acute trauma, exsanguination, and not having basic cardiopulmonary resuscitation for >10 …