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Q Are routine rotavirus vaccinations (3 times/infant) cost effective in the US?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Paediatrics (general) ★★★★★★☆ Public health ★★★★★★☆
cost effectiveness study using a probabilistic (Monte Carlo) model.
nationwide in the US.
a hypothetical cohort of 4 010 000 children monitored from 0 to 59 months of age.
routine vaccinations for infants at 2, 4, and 6 months of age with a pentavalent human bovine reassortant rotavirus vaccine (PVR) (RotaTeq; Merck, Whitehouse Station, NJ, USA) or no vaccinations.
deaths, hospital admissions, emergency department visits, office visits, and episodes with home care; and the cost effectiveness ratio per case (any disease) averted, per serious case (hospital admission, …
For correspondence: Dr M A Widdowson, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Source of funding: Centers for Disease Control and Prevention.