Article Text
Therapeutics
Prednisolone plus paracetamol (acetaminophen) was as effective as indomethacin plus paracetamol but had fewer adverse effects in acute gout-like arthritis
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Man CY, Cheung IT, Cameron PA, et al. Comparison of oral prednisolone/paracetamol and oral indomethacin/paracetamol combination therapy in the treatment of acute goutlike arthritis: a double-blind, randomized, controlled trial. Ann Emerg Med 2007;49:670–7.
Clinical impact ratings GP/FP/Primary care ★★★★★★⋆ IM/Ambulatory care ★★★★★★★ Emergency medicine ★★★★★★⋆ Rheumatology ★★★★★⋆⋆
METHODS
Design:
randomised placebo controlled trial.
Allocation:
{concealed}*.†
Blinding:
blinded (patients and {healthcare providers}*).†
Follow-up period:
14 days.
Setting:
an emergency department (ED) of a large teaching hospital in Hong Kong, China.
Patients:
90 patients >17 years of age (mean age 65 y, 82% men) with acute gouty arthritis who presented to the ED within 3 days of pain onset and had ⩾1 …