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Aetiology
Subclavian stenosis was associated with an increase in all-cause and cardiovascular mortality at a mean of 9.4 years

http://dx.doi.org/10.1136/ebm.13.1.25

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    V Aboyans

    Dr V Aboyans, University of California-San Diego, La Jolla, CA, USA; vaboyans@ucsd.edu

    STUDY QUESTION

    Is subclavian stenosis associated with increased all-cause and cardiovascular (CV) mortality?

    STUDY DESIGN

    Design:

    cohort study including 3 cohorts.

    Setting:

    2 vascular laboratories in San Diego, California; 3 medical centres (2 vascular laboratories, 1 general medicine clinic) in Chicago, Illinois; and a community-dwelling cohort in southern California, USA.

    Participants:

    1778 participants (mean age 69 y, 62% men), two-thirds of whom received lower extremity arterial testing. Exclusion criteria included being bound to a wheelchair; living in a nursing home; and having dementia, amputations, or an ankle-brachial index >1.50 (in the second cohort).

    Risk factors:

    subclavian stenosis (presence of brachial systolic pressure difference ⩾15 …

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    Footnotes

    • Source of funding: National Institutes of Health; National Heart, Lung and Blood Institute; National Center for Research Resources; American Heart Association.