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Therapeutics
Review: vitamin D supplementation decreases all-cause mortality in adults and older people

https://doi.org/10.1136/ebm.13.2.47

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    P Autier

    Dr P Autier, International Agency for Research on Cancer, Lyon, France; autierp@iacr.fr

    REVIEW PROCESS

    Question:

    what is the effect of vitamin D supplementation on all-cause mortality?

    Search methods:

    PubMed, ISI Web of Science (Science Citation Index Expanded), EMBASE/Excerpta Medica, Cochrane Library, and bibliographies of selected studies, reviews, or books (to November 2006).

    Study selection and assessment:

    principal published reports of randomised controlled trials (RCTs) that assessed the effects of vitamin D supplementation (vitamin D2 [ergocalciferol] or vitamin D3 [cholecalciferol]), taken for any condition, on all-cause mortality. Trials had to randomise participants on an individual (rather than cluster) basis and include sufficient information to allow for calculation of relative risks and 95% CIs for all-cause mortality for vitamin D supplementation v placebo or control. …

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    Footnotes

    • Source of funding: not stated.