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Non-diabetic maternal hyperglycaemia was associated with adverse pregnancy outcomes

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B E Metzger

Dr B E Metzger, Northwestern University Feinberg School of Medicine, Chicago, IL, USA;


Is non-diabetic maternal hyperglycaemia associated with adverse pregnancy outcomes?



cohort study (Hyperglycemia and Adverse Pregnancy Outcome [HAPO] study) with follow-up to delivery.


15 centres in the US, Canada, Barbados, UK, the Netherlands, Israel, Thailand, Hong Kong, Singapore, and Australia.


25 505 women ⩾18 years of age (mean age 29 y) who were pregnant with a singleton fetus of known gestational age …

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  • Source of funding: Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; American Diabetes Association.