Article Text
Therapeutics
Intensive glucose control increased mortality and did not prevent cardiovascular events in type 2 diabetes
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R P Byington
Dr R P Byington, Wake Forest University School of Medicine, Winston-Salem, NC, USA; bbyingto@wfubmc.edu
STUDY DESIGN
Design:
randomised controlled trial (Action to Control Cardiovascular Risk in Diabetes [ACCORD]).
Allocation concealment:
concealed.*
Blinding:
blinded (outcome adjudication committee and laboratory staff).*
STUDY QUESTION
Setting:
77 centres in the USA and Canada.
Patients:
10 251 patients 40–79 years of age (mean age 62 y, 61% …
Footnotes
Source of funding: National Institutes of Health; Centers for Disease Control and Prevention; General Clinical Research Centers.