You are here

Article Text

Article menu
Download PDFPDF
Therapeutics
Early, abrupt weaning did not reduce risk of HIV infection or mortality in breast-fed infants of mothers with HIV

https://doi.org/10.1136/ebm.13.6.182

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    L Kuhn

    Dr L Kuhn, Columbia University, New York, NY, USA; lk24@columbia.edu

    STUDY DESIGN

    Design:

    randomised controlled trial.

    Allocation:

    {concealed}†.*

    Blinding:

    unblinded.*

    STUDY QUESTION

    Setting:

    2 antenatal clinics in Lusaka, Zambia.

    Patients:

    958 women (mean age 26 y) who had HIV, were enrolled during pregnancy and planned to breast feed, accepted treatment with nevirapine, and were still breast feeding 1 month after birth. Exclusion criteria were severe pregnancy complications, past caesarean delivery, or hospital admission for HIV-related conditions.

    Intervention:

    counselling intervention (n = 481), which encouraged women to breast feed exclusively for 4 months and then cease breast feeding abruptly, or standard care (n = 477), where women were encouraged to breast feed exclusively for 6 months, and then continue as long as they wished, with gradual …

    View Full Text

    Footnotes

    • Source of funding: National Institute of Child Health and Human Development; Centers for Disease Control and Prevention; Agency for International Development; Stephen Lewis Foundation.