The following articles were abstracted in the September and October 2008 issues of ACP Journal Club. The declarative title of each abstract as published in ACP Journal Club precedes the article citation.

THERAPEUTICS

• Review: Nonergot dopamine agonists reduce symptoms but may be discontinued for adverse events in restless legs syndrome

Baker WL, White CM, Coleman CI. Effect of nonergot dopamine agonists on symptoms of restless legs syndrome. Ann Fam Med 2008;6:253–62.

• Adding single-point acupuncture to physiotherapy for painful shoulder improved function and reduced pain

Vas J, Ortega C, Olmo V, et al. Single-point acupuncture and physiotherapy for the treatment of painful shoulder: a multicentre randomized controlled trial. Rheumatology (Oxford) 2008;47:887–93.

• An intervention involving pharmacist care via the Web improved blood pressure control in uncontrolled hypertension

Green BB, Cook AJ, Ralston JD, et al. Effectiveness of home blood pressure monitoring, Web communication, and pharmacist care on hypertension control: a randomized controlled trial. JAMA 2008;299:2857–67.

• Rhythm control and rate control did not differ for CV mortality in atrial fibrillation and congestive heart failure

Roy D, Talajic M, Nattel S, et al. Rhythm control versus rate control for atrial fibrillation and heart failure. N Engl J Med 2008;358:2667–77.

• Thromboprophylaxis with rivaroxaban or enoxaparin did not differ for major bleeding and other safety outcomes in hip arthroplasty

Eriksson BI, Borris LC, Friedman RJ, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med 2008;358:2765–75.

• Thromboprophylaxis with rivaroxaban or enoxaparin did not differ for major bleeding in knee arthroplasty

Lassen MR, Ageno W, Borris LC, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008;358:2776–86.

• Low-dose vasopressin did not reduce mortality more than norepinephrine in septic shock

Russell JA, Walley KR, Singer J, et al. Vasopressin versus norepinephrine infusion in patients with septic shock. N Engl J Med 2008;358:877–87.

• Prasugrel reduced ischemic outcomes and stent thrombosis more than did clopidogrel in patients with ACS who received stents

Wiviott SD, Braunwald E, McCabe CH, et al. Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial. Lancet 2008;371:1353–63.

• Multidetector computed tomography alone or with venous ultrasonography of the leg were noninferior for excluding PE

Righini M, Le Gal G, Aujesky D, et al. Diagnosis of pulmonary embolism by multidetector CT alone or combined with venous ultrasonography of the leg: a randomised non-inferiority trial. Lancet 2008;371:1343–52.

• Bivalirudin reduced major bleeding and adverse events in patients with STEMI undergoing primary PCI

Stone GW, Witzenbichler B, Guagliumi G, et al. Bivalirudin during primary PCI in acute myocardial infarction. N Engl J Med 2008;358:2218–30.

• Intensive insulin therapy improved glycemic control more than oral hypoglycemic agents in newly diagnosed type 2 diabetes

Weng J, Li Y, Xu W, et al. Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial. Lancet 2008;371:1753–60.

• Review: Mifepristone is more effective for emergency contraception than levonorgestrel

Cheng L, Gülmezoglu A, Piaggio G, et al. Interventions for emergency contraception. Cochrane Database Syst Rev 2008;(2):CD001324.

DIAGNOSIS

• Review: Spot protein–creatinine ratio has moderate diagnostic performance for proteinuria in pregnant women with hypertension

Côté AM, Brown MA, Lam E, et al. Diagnostic accuracy of urinary spot protein:creatinine ratio for proteinuria in hypertensive pregnant women: systematic review. BMJ 2008;336:1003–6.

• Review: 64-slice computed tomography coronary angiography accurately diagnoses coronary artery disease

Stein PD, Yaekoub AY, Matta F, et al. 64-slice CT for diagnosis of coronary artery disease: a systematic review. Am J Med 2008;121:715–25.

CLINICAL PREDICTION GUIDE

• A screening model was effective for detecting tuberculosis in contact patients

Aissa K, Madhi F, Ronsin N, et al. Evaluation of a model for efficient screening of tuberculosis contact subjects. Am J Respir Crit Care Med 2008;177:1041–7.