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Therapeutics
Benefits of tight blood pressure control to prevent diabetes complications were not sustained

https://doi.org/10.1136/ebm.14.1.10

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    R R Holman

    Dr R R Holman, Diabetic Trials Unit, Oxford, UK; rury.holman@dtu.ox.ac.uk

    STUDY DESIGN

    Design:

    randomised controlled trial (Hypertension in Diabetes Study) within the UK Prospective Diabetes Study (UKPDS). Current Controlled Trials ISRCTN75451837.

    Allocation:

    {concealed}*.†

    Blinding:

    blinded (outcome adjudication committee).†

    STUDY QUESTION

    Setting:

    {20}* centres in the UK.

    Patients:

    1148 patients {mean age 56 y, 56% men}* with type 2 diabetes who were already participating in the UKPDS and had hypertension. Exclusion criteria included …

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    Footnotes

    • Source of funding: UK Medical Research Council; UK Department of Health; Diabetes UK; British Heart Foundation; UK National Institute for Health; 6 drug companies.