Statistics from Altmetric.com
Professor M Underwood, University of Warwick, Coventry, UK; M.Underwood@warwick.ac.uk
randomised controlled trial (Topical or Oral Ibuprofen [TOIB]).
blinded (data collectors).*
26 general practices in the UK.
282 patients ⩾50 years of age (mean age 63 y, 54% women) with knee pain (97% with osteoarthritis). Exclusion criteria included history of, or awaiting, knee replacement, and recent knee injury.
the patient’s general practitioner prescribed or recommended preferential use of over-the-counter topical ibuprofen, applied according to manufacturer’s instructions (eg, 0.5 g per knee up to 3 times/d, equivalent to 75 mg/d of ibuprofen using a 5% preparation) (n = 138), or oral ibuprofen, up to 1.2 g/day (n = 144). Increased dose, …
Source of funding: Health Technology Assessment Programme; Goldshield Pharmaceuticals supplied starter packs of topical ibuprofen.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.