Article Text

Download PDFPDF
Review: an early invasive strategy has similar benefits in men and women with NSTEMI or unstable angina

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

M O’Donoghue

Dr M O’Donoghue, Brigham and Women’s Hospital, Boston, MA, USA;


In patients with non–ST-segment elevation myocardial infarction (NSTEMI) or unstable angina, does an early invasive strategy, compared with a conservative strategy, have similar benefits in men and women?


Included studies compared an early invasive strategy (immediate coronary angiography followed by revascularisation if appropriate) with a conservative strategy (primary pharmacological management with coronary angiography reserved for patients with recurrent ischaemia) in patients with NSTEMI or unstable angina. Studies were excluded if fibrinolytic therapy was administered to all patients or coronary angiography was required before enrolment. Outcomes were death, non-fatal MI, hospital readmission for acute coronary syndrome, and a composite of these 3 outcomes.


Medline and Cochrane Library (to …

View Full Text


  • Source of funding: no external funding.