Article Text
Prognosis
Review: long-term annual conversion rate to dementia was 3.3% in elderly people with mild cognitive impairment
Statistics from Altmetric.com
QUESTION
In elderly people with mild cognitive impairment (MCI), what is the long-term rate of conversion to dementia?
REVIEW SCOPE
Included studies examined the progression of MCI, defined according to accepted criteria. Outcomes were dementia or probable Alzheimer disease.
REVIEW METHODS
Medline, EMBASE/Excerpta Medica, and PsycINFO (to Mar 2008) were searched for cohort studies with ⩾5 years of follow-up. 15 studies (n = 2404, mean age 62–82 y) met the selection criteria. Mean follow-up was 6 years (range 5–10 y).
MAIN RESULTS
The cumulative conversion rate to dementia was 31% (15 studies) and to Alzheimer disease was 33% (11 studies). The table shows annual conversion rates. …
Footnotes
Source of funding: no external funding.