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A simple clinical score accurately identified patients who had a cardiac cause of syncope

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Does the Evaluation of Guidelines in Syncope Study (EGSYS) score accurately identify patients in the emergency department (ED) with a cardiac cause of syncope?



prospective cohort study.


EDs of 14 general hospitals in Italy.


516 adults (mean age 63 y, 54% men) who presented to the ED within 24 hours of transient loss of consciousness, initially ascribed to a syncopal condition. Patients were divided into derivation (n = 260) and validation (n = 256) cohorts.

Description of prediction guide:

the EGSYS score consists of the 6 (out of 52) items found to be most predictive of a cardiac cause of syncope: palpitations preceding syncope (4 points), history of heart disease or abnormal electrocardiogram in the ED (3 points), syncope during effort (3 …

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  • Source of funding: Gruppo Italiano per lo Studio della Sincope.